The protagonist, Yang Yifan, is a surgical prodigy at a top-tier hospital. After an accident, he transmigrates to the Ming Dynasty and is mistaken for a heretical demon, nearly getting his head chopped off.
With his superb medical skills and bizarre modern knowledge, such as handwashing, sterilization, stethoscopes, and CPR, he turns his fortunes around step by step and is recommended for an apprenticeship at the Imperial Medical Bureau.
Hilarious incidents keep piling up. Teaching people to rinse their mouths gets him accused of practicing sorcery; lighting a fire with a lighter makes people think he is an immortal; and after treating a eunuch's loss of voice, he gets chased by people shouting, “Divine doctor, give us your medicine!”
He uses modern surgical techniques to save a prince who has been gravely injured, earning his trust and officially entering the imperial medical system.