While reading ancient medical books in the laboratory, Yang Duoduo was struck by mysterious lightning and traveled to the Republic of China, penniless and without any relatives. Fortunately, Gu Yichen helped her and took her back home, starting her life in the Gu family. She uses modern medical knowledge to treat illnesses, which arouses the curiosity of the Gu family and the suspicion of the housekeeper.
With Gu Yichen's support, Yang Duoduo opened a clinic to provide free diagnosis and treatment to poor people. As his reputation gradually grew, the relationship between the two warmed up. However, when the war came, Gu Yichen's family business encountered a crisis, and he was ordered to go elsewhere to deal with it. Yang Duoduo stayed at the clinic alone, struggling to cope with difficulties such as lack of supplies. During this period, Su Ran appeared to help provide medicinal materials and help in the clinic. Although her confession was rejected, she still guarded her silently.
Later, Gu Yichen returned and brought supplies to alleviate the crisis in the clinic. But at this time, the clinic's medicines were stolen and the Gu family's business was suppressed. They discovered that Japanese spies were behind it. With the help of Su Ran, the three of them worked together to investigate, went through difficulties and obstacles, and finally succeeded in exposing the Japanese spy conspiracy.
After the war, they devoted themselves to reconstruction work, expanded their clinics, opened medical schools, and trained many medical talents. During the process, although problems such as funding, talent, and opposition from conservative forces were faced, they were all overcome one by one. The relationship between Gu Yichen and Yang Duoduo also went through many tests, and they were finally recognized by their families and held a wedding. Since then, they have devoted themselves to the development of medicine, and the medical school has continued to grow. Their stories have become legends, passed down from generation to generation in the local area, inspiring countless descendants to devote themselves to medicine. Their spirit has also become a symbol of local culture and has far-reaching influence.