During the Chenghua period of the Ming Dynasty, there was a rumor in the world that "the Gu Hong Sword came out and the world changed hands." A Guhong sword that contains clues to a treasure from the previous dynasty caused a bloody storm in the martial arts world. Ye Guhong, the young master of Tianji Pavilion, was rescued by a mysterious man on the night when the sect was destroyed. He was burdened with blood feud and sword skills, and embarked on the road to pursue the truth.
Ten years later, he transformed into a wandering doctor and sneaked into the Jianghu, but he was involved in the pursuit of the six gates, the poisonous poison conspiracy in the Netherworld Valley, and the power struggle between business gangs in the Western Regions. When he discovers that the massacre of his family is actually related to the court's "Tian Luo" organization, he must choose between martial arts morality and the justice of his family and country. And the real secret of Gu Hongjian actually points to a centuries-old plan to subvert the martial arts of the Central Plains...