When a series of murders such as a hotel corpse case and a shopping mall blood sacrifice case spanned seven provinces, the police were always misled by contradictory biological evidence: left-handed and right-handed people appeared alternately, DNA pointed to the dead person, and the murderer on surveillance appeared in two places thousands of miles apart at the same time. When Chen Guodong discovered that all the victims had left records in a children's welfare home, the dusty files revealed the past of the twins Wu Ming/Wu Liang who were adopted by a perverted professor - the elder brother was trained to be a logic machine, and the younger brother was cultivated to be an artistic paranoid. This cat-and-mouse game spanning ten years is actually a twisted dialogue performed by the twins with blood. In the end, Chen Guodong took advantage of the creative differences between the brothers and started a psychological game with the twins in the specimen room of the mental hospital, using twenty years of criminal investigation notes to break the mirror image puzzle of the perfect crime.