Su Li transmigrates into the body of a concubine-born daughter. She should have lived a quiet, unremarkable life, but her extraordinary talents in medicine and poison make that impossible. With a single silver needle, she can heal the sick and save lives, or strike a fatal blow. Newly reborn, she is swept into her family's power struggles and palace intrigue. In the depths of the palace, amid shifting political tides and deadly scheming, she holds the reins. Fate propels her ever higher: she becomes a thorn in the side of powerful ministers and the one person Emperor Xiao Qi cannot stop thinking about. Torn between politics and love, Su Li rises from obscurity to take command at the very heart of power. She heals with medicine and defeats her enemies with poison, using her intelligence and ruthless methods to win the respect and command of the realm.
This is the story of a woman who uses medicine and poison, courage and cunning, to rise against all odds, become a ruler, and master the game of power. Amid the shifting fortunes of the realm, how will the imperial physician consort triumph from a thousand miles away and become a legend revered by all?
