Naruto: The Hyuga Main Family, Six Eyes from the Start

Twelve years ago, a white-haired descendant with naturally blue eyes was born into the conservative, stern Hyuga Main Family.

He was unruly and treated the clan rules as meaningless, giving the members of the Main Family no end of trouble.

Hyuga Hiashi: “A bloodline disease, perhaps… Someone like you will never make it to the other side.”

Many years later.

Hyuga Hiashi: “The… the Byakugan can evolve?!”