The purpose of this book is to guide veterinary workers to more systematically understand new technologies for animal disease sample collection, master commonly used new methods, improve sample collection levels, enhance technical support for animal epidemic prevention work, especially the prevention and control of major animal diseases, and provide strong technical support for protecting the healthy development of the animal husbandry industry. This manual focuses on clarifying the basic principles and requirements for sample collection in animal laboratories, the preliminary preparation, basic methods and precautions for sample collection, the preservation, packaging and transportation of samples, and the organisms when collecting samples. It involves the basic content of standardized sample collection in animal laboratories. It plays an important role in guiding the basic content of standardized sample collection in animal laboratories and the work of animal laboratory technicians or other veterinary workers.