The story follows Su Yao, a once-vibrant young woman. In a reckless moment after a breakup, Su Yao has unprotected sex with a stranger, unaware that this seemingly ordinary encounter will drag her into an abyss.
Afterward, her health begins to deteriorate. She falls ill frequently and suffers from extreme fatigue. A comprehensive examination confirms that she has AIDS, and the news hits her like a bolt from the blue. Plunged into deep self-blame and boundless fear, she also finds that people around her have begun to look at her differently.
At the hospital, she meets Professor Li’s team, who are researching AIDS treatment and searching for a new breakthrough. Su Yao becomes the brightest hope for their new treatment plan. As she fights the disease, she gradually grows stronger after her initial collapse. She knows she must fight for a chance to be reborn, and for the people who still love her.