It tells the story of Li Lange, a descendant of a family of ancient medicine, who after traveling through time and becoming a beggar, relied on his superb medical skills to establish himself in Jinling City. She was rescued by Prince Baili Chenjin in Hongyuan Tower, and became a disciple of Chief Physician Xu Feng and entered Tai Hospital. In the palace, she was repeatedly challenged by Xiao Yanling, but she also showed extraordinary talents in treating diseases. Later, a plague broke out in the capital, and she and Baili Chenjin went there for treatment. In the process, the two gradually fell in love and worked together to overcome many difficulties. With his wisdom and medical skills, Li Lange not only saved many people, but also resolved a series of palace crises, and finally gained love and growth.