When Du Hao, a doctor at the Provincial Hospital, looked at his blood vessel cancer cell samples through a microscope, he saw a man in black inside the blood vessels and ordered him to kill his father. Previously, his single father used an ancestral book to teach Du Hao to practice magic and cure his son's cancer, but he was killed. Du Hao found a small bronze mirror when digging a temporary grave for his father, and then traveled to the Ming Dynasty. He must cultivate to become a top spiritual blood master and destroy the Cancer Demon Sect in order to curb the spread of cancer, resurrect his parents, and save the Ming Dynasty. When he embarked on the road of cultivation with a near-death experience, a shocking conspiracy had begun...