Yang Yizhong was born with a Buddhist affinity. When he was young, he became a monk at Guangpu Temple in Songzhou and discovered the shocking secrets in the temple. In order to save the abbot, he risked his life and went to the Yaowang Valley alone to find the antidote. On the way, he was captured by the Blue Lotus Sect. Through some strange combination of circumstances, he was favored by the leader of the Yaowang Temple. Gu was in danger several times, but inadvertently developed a unique martial arts that was invulnerable to all poisons. He was entrusted by the Poison King He Miaoshou to take care of his daughter He Saifeng, and completed the "Medicine Economics" that He Miaoshou had planned to complete. He Saifeng fell in love with Yang Yizhong while getting along with him. In order to restore his country, the prince of Mozang King disguised himself as a monk and went to the Central Plains to find three magic weapons on the pretext of studying Buddhism among the monks of the Shenxiu clan of the Northern Sect. He did not hesitate to kill for this purpose. Chances and coincidences were intertwined with the whereabouts of Yang Yizhong. In order to avoid the loss of life and prevent the prince of Mozang King from getting the magic weapon, Yang Yizhong started a fight. His beloved also died and walked away because of it. In the end, he defeated evil and achieved righteousness.