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The modern Guizhou Chamber of Commerce was established under the top-down promotion of the late Qing government. Since its creation, it has become the driving force for Guizhou's economic and social development. In terms of economy, the Chamber of Commerce has promoted the transformation and upgrading of modern Guizhou's economy by assisting enterprises with financing, providing various information for free, participating in expositions, setting up power plants, applying for tax reductions for industrial and commercial enterprises, rectifying market order, investigating rural economic information, promoting improved varieties and cash crops, solving problems in the transportation and marketing of rural handicrafts and agricultural products, and establishing a "quality and safety" system for agricultural products and a "joint venture" system for agricultural products. In terms of education, the Chamber of Commerce establishes basic education, develops vocational education, establishes higher education, and participates in social education. In addition to directly running schools, the Chamber of Commerce made donations to schools, donated teaching equipment and books, and donated libraries to build libraries, etc., Which promoted the reform and development of education in Guizhou in modern times. In terms of regional public utilities, the Chamber of Commerce participated in dredging rivers, raising funds for modern water and land transportation construction, establishing fire brigades, and relieving victims and refugees, etc., Promoting the modernization of Guizhou's public utilities. The Guizhou Chamber of Commerce in modern times was also an important force in resisting foreign invasion and defending modern China's international rights. During the Japanese invasion of China, the Chamber of Commerce not only participated in the boycott of Japanese goods, developed domestic products, made donations, subscribed for public bonds, and expressed condolences to the soldiers and their families during the Anti-Japanese War, and called on businessmen to actively implement the national government's wartime economic policies. It also linked up with the Vietnam Chinese Chamber of Commerce to urge the French government to assume its treaty obligation to allow China to transit through French Vietnam.