Drug Synthesis Technology (Second Edition)

Drug synthesis technology is one of the most important professional courses in pharmaceutical majors. This textbook is based on comprehensively improving students' quality, with professional construction as the core, and ability-oriented organization. The content is properly selected and the practice link is strengthened. The book is divided into eleven chapters. The content takes the typical drug synthesis process as an example and systematically introduces the basic content of drug preparation, basic practical techniques and production processes, as well as pharmaceutical reaction equipment and environmental protection and safety knowledge. The book combines aspirin, acetaminophen, norfloxacin, sulfamethoxazole, chloramphenicol, hydrocortisone, semi-synthetic penicillins, semi-synthetic cephalosporins, paclitaxel, vitamin C and other typical drugs, and conducts detailed discussions on the acylation reaction technology, reduction reaction technology, halogenation reaction technology, alkylation reaction technology, condensation reaction technology, oxidation reaction technology, fermentation pharmaceutical technology, solvent and catalyst application technology, and chiral drug synthesis technology involved in drug synthesis. Add operation and operation content to the production technology part, and combine it with specific laboratory operations to strengthen students' perceptual understanding and practical skills training, so that practical teaching can be integrated into theoretical teaching. This book covers a wide range of topics, moves from the shallower to the deeper, and is highly practical. It can be used not only as a professional textbook on pharmaceutical production technology in higher vocational colleges, but also as a reference for related majors and production, technology, and management personnel.