Yun Qianshang, a prodigy of ancient medicine in the twenty-first century, transmigrates and becomes the unlucky daughter of a concubine in the Prime Minister's household. The First Madam has burned her face, and she is forced to take the place of her legitimate elder sister and marry the Eighth Prince.
Faced with such a predicament, she gives a cold laugh. On their wedding day, she gets the Eighth Prince back on his feet and out of his coffin.
From then on, the Prime Minister's supposedly weak and useless concubine-born daughter changes completely. Everyone who has offended her ends up inexplicably poisoned, their bodies rotting away until they die.
One day, good news spreads from the Eighth Prince's residence: the chronically ill prince has suddenly recovered...