Murong Qingcheng, the adopted daughter of the great general Murong of Western Shu, is reborn in the body of Murong Qingcheng, an illegitimate daughter of a Northern Qi official. Imprisoned, she endures torture and humiliation. To avenge her family's slaughter, she attaches herself to the ambitious Third Young Master Chu, becoming his pawn and infiltrating the Northern Qi imperial palace. To achieve her revenge, Murong Qingcheng plays both sides with Third Young Master Chu while searching for an ally of her own: the overlooked Fourth Prince, Tuoba Gui. Step by step, she helps Tuoba Gui ascend the throne, becomes the consort of Northern Qi, and launches a war against Western Shu. At the foot of the steps, she watches her enemies bow before her. The Poisonous Empress Murong Qingcheng finally gets the revenge she has long desired.